Overall Net-Zero Target INTEGRA Biosciences Holding AG commits to reach net-zero GHG emissions across the value chain by 2050 from a 2021 base year. Near-Term Targets INTEGRA Biosciences Holding AG commits to reduce absolute scope 1 and 2 GHG emissions 46.2% by 2031 from a 2021 base year. INTEGRA Biosciences Holding AG also commits to increase active annual sourcing of renewable electricity from 48% in 2021 to 100% by 2030. INTEGRA Biosciences Holding AG further commits to reduce scope 3 GHG emissions from purchased goods and services, fuel and energy related activities, upstream transportation & distribution, waste generated in operations, business travel, employee commuting, use of sold products, and end-of-life treatment of sold products 51.6% per million CHF value added by 2029 from a 2019 base year. Long-Term Targets INTEGRA Biosciences Holding AG commits to reduce absolute scope 1 and 2 GHG emissions 90% by 2050 from a 2021 base year. INTEGRA Biosciences Holding AG commits to reduce scope 3 GHG emissions 97% per million CHF value added within the same timeframe.